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Comparative Study
. 2013 Feb;31(2):99-104.
doi: 10.1007/s11604-012-0153-9. Epub 2012 Oct 19.

Dual-energy perfusion CT of non-diseased lung segments using dual-source CT: correlation with perfusion SPECT

Yoshie Kunihiro  1 , Munemasa Okada, Naofumi Matsunaga, Yuichi Sano, Shohei Kudomi, Kazuyoshi Suga, Shoji Kido
Affiliations
Comparative Study

Dual-energy perfusion CT of non-diseased lung segments using dual-source CT: correlation with perfusion SPECT

Yoshie Kunihiro et al. Jpn J Radiol. 2013 Feb.

Abstract

Purpose: To determine the utility of dual-energy perfusion CT (DEpCT) of non-diseased lung segments, using dual-source CT, in comparison with perfusion single-photon emission computed tomography (SPECT).

Materials and methods: 28 patients (18 male and 10 female; mean age 63 years; age range 18-86 years) underwent DEpCT and SPECT within a 3-day interval. The presence and location of perfusion defects in each segment of the lungs were evaluated.

Results: Perfusion defects were noted in 7 of 361 segments (1.9%) by DEpCT and in 19 of 361 segments (5.3%) by perfusion SPECT. DEpCT was in good agreement with perfusion SPECT for 338 of 361 segments (93.6%). Intraobserver agreement was also good, ranging from 93.4 to 93.6% (κ = 0.64-0.75, p < 0.01).

Conclusion: For non-diseased lung segments, DEpCT correlated well with SPECT.

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