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Comparative Study
. 2012 Sep;30(3):366-70.
doi: 10.3329/jhpn.v30i3.12300.

Changing pattern of dengue virus serotypes in Thailand between 2004 and 2010

Piyathida Pongsiri  1 , Apiradee Themboonlers, Yong Poovorawan
Affiliations
Comparative Study

Changing pattern of dengue virus serotypes in Thailand between 2004 and 2010

Piyathida Pongsiri et al. J Health Popul Nutr. 2012 Sep.

Abstract

Dengue virus infection is a major concern in several countries, and more than 50 million people are infected worldwide each year. Thailand is one of the countries where people are susceptible to infection due to favourable geographical and environmental conditions. In this retrospective study, we reported the changing pattern of dengue virus serotypes during the period between 2004 and 2010. The following percentage prevalence showed different serotypes of dengue virus (DENV) predominant in respective years: DENV1 in 2004 (56.41%), DENV4 in 2007 (50%), DENV1 in 2008 (57.41%), and DENV3 in 2010 (38.7%). Moreover, the major serotypes were not stable as they showed a shift from one serotype to another. We also found co-infection with two different serotypes and reported the clinical manifestations, which were not different from infection with a single serotype. Co-infection with various serotypes may not necessarily cause more severe disease.

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Figures

Fig. 1.
Fig. 1.
Comparison of different serotypes of dengue-infection in Thai patients during 2004-2010
Fig. 2.
Fig. 2.
Gel-electrophoresis of PCR products after semi-nested PCR showing DENV3 of 417 bp and DENV4 of 358 bp
See this image and copyright information in PMC

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