Review
doi: 10.1586/ern.12.120.
Primary CNS lymphoma: a clinician's guide
Affiliations
- PMID: 23082736
- DOI: 10.1586/ern.12.120
Item in Clipboard
Review
Primary CNS lymphoma: a clinician's guide
Expert Rev Neurother.
2012 Oct.
Abstract
Primary CNS lymphoma is a high malignant disease of the brain which can lead rapidly to death if diagnosis and/or the start of treatment is delayed. The age at time of diagnosis is a strong factor influencing prognosis so that in younger patients <65 years of age long-term survival may be achieved in a substantial percentage of patients, while in elderly patients long-term survival is seen much more rarely. First-line therapy consists of high-dose methotrexate-based (poly)chemotherapy. This review provides an overview of clinical presentation, steps to diagnosis, detailed information about current treatment concepts and specific information for particular clinical situations.
Similar articles
-
Primary CNS lymphoma.Expert Rev Anticancer Ther. 2007 May;7(5):689-700. doi: 10.1586/14737140.7.5.689. Expert Rev Anticancer Ther. 2007. PMID: 17492932 Review.
-
Primary non-Hodgkin's lymphoma of the CNS treated with CHOD/BVAM or BVAM chemotherapy before radiotherapy: long-term survival and prognostic factors.Int J Radiat Oncol Biol Phys. 2004 Jun 1;59(2):501-8. doi: 10.1016/j.ijrobp.2003.11.001. Int J Radiat Oncol Biol Phys. 2004. PMID: 15145169
-
Secondary central nervous system (CNS) involvement in patients with diffuse large B-cell lymphoma: a therapeutic dilemma.Ann Hematol. 2011 May;90(5):539-46. doi: 10.1007/s00277-010-1104-0. Epub 2010 Oct 20. Ann Hematol. 2011. PMID: 20960190
-
[Primary central nervous system lymphoma: diagnosis, management and current topics].No To Shinkei. 2004 Mar;56(3):195-203. No To Shinkei. 2004. PMID: 15112444 Review. Japanese. No abstract available.
-
Treatment for primary CNS lymphoma: the next step.J Clin Oncol. 2000 Sep;18(17):3144-50. doi: 10.1200/JCO.2000.18.17.3144. J Clin Oncol. 2000. PMID: 10963643 Clinical Trial.
Cited by
-
Predictive value of microRNAs as novel biomarkers in detection of lymphoma.Int J Clin Exp Med. 2015 Aug 15;8(8):14479-89. eCollection 2015. Int J Clin Exp Med. 2015. PMID: 26550438 Free PMC article.
-
Serum miR-21 is a diagnostic and prognostic marker of primary central nervous system lymphoma.Neurol Sci. 2014 Feb;35(2):233-8. doi: 10.1007/s10072-013-1491-9. Epub 2013 Jul 6. Neurol Sci. 2014. PMID: 23832112
-
Identification of miRNAs as potential new biomarkers for nervous system cancer.Tumour Biol. 2014 Nov;35(11):11631-8. doi: 10.1007/s13277-014-2387-x. Epub 2014 Aug 20. Tumour Biol. 2014. PMID: 25139093
-
Hyperosmolar and methotrexate therapy avoiding surgery in the acute presentation of primary central nervous system lymphoma.Surg Neurol Int. 2014 Jul 16;5(Suppl 4):S175-80. doi: 10.4103/2152-7806.136741. eCollection 2014. Surg Neurol Int. 2014. PMID: 25184099 Free PMC article.
-
Lymphomatosis cerebri mimicking iatrogenic Creutzfeldt-Jakob disease.BMJ Case Rep. 2014 Sep 8;2014:bcr2013201246. doi: 10.1136/bcr-2013-201246. BMJ Case Rep. 2014. PMID: 25199185 Free PMC article.
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Medical
