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Review
. 2012 Oct;22(4):661-77.
doi: 10.1016/j.giec.2012.07.004. Epub 2012 Aug 20.

Diagnosis of celiac disease

Benjamin Lebwohl  1 , Alberto Rubio-Tapia, Asaad Assiri, Catherine Newland, Stefano Guandalini
Affiliations
Review

Diagnosis of celiac disease

Benjamin Lebwohl et al. Gastrointest Endosc Clin N Am. 2012 Oct.

Abstract

This article reviews issues related to identifying the appropriate patient to test for celiac disease, the performance characteristics of serologic testing, the role of gene testing for human leukocyte antigen DQ2 and DQ8 haplotypes, and issues related to the performance of small intestinal biopsy. The article concludes with a review of special diagnostic considerations in pediatric patients.

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Figures

FIGURE 1
FIGURE 1
Mayo Clinic Celiac Disease Diagnostic Testing Algorithm. Serology and genetic testing are part of an automated laboratory cascade testing, meaning that a sequence of tests driven by real time results is used to diagnose celiac disease using a single blood draw. This cascade testing is intended for adults on a gluten-containing diet. (Modified and used by permission of Mayo Foundation for Medical Education and Research. All rights reserved).
See this image and copyright information in PMC

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