Secreted bacterial vesicles as good samaritans
- PMID: 23084908
- DOI: 10.1016/j.chom.2012.10.005
Secreted bacterial vesicles as good samaritans
Abstract
Bacteriodes fragilis and polysaccharide A capsular antigen (PSA) produced by this commensal bacteria can mediate immune tolerance in the gastrointestinal (GI) tract. When looking for naturally secreted forms of PSA, Shen et al. (2012) suprisingly found that PSA is packaged in outer membrane vesicles (OMVs), bacterial blebs with a disreputable past.
Copyright © 2012 Elsevier Inc. All rights reserved.
Comment on
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Outer membrane vesicles of a human commensal mediate immune regulation and disease protection.Cell Host Microbe. 2012 Oct 18;12(4):509-20. doi: 10.1016/j.chom.2012.08.004. Epub 2012 Sep 20. Cell Host Microbe. 2012. PMID: 22999859 Free PMC article.
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