Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Comment
. 2013 Jan 21:317:422-4.
doi: 10.1016/j.jtbi.2012.10.017. Epub 2012 Oct 22.

Improved patient-specific calibration for agent-based cancer modeling

Alice Z Hyun, Paul Macklin
Comment

Improved patient-specific calibration for agent-based cancer modeling

Alice Z Hyun et al. J Theor Biol. .
No abstract available

PubMed Disclaimer

Figures

Fig. 1.
Fig. 1.. Comparison of calibration methods:
We compare the simulated (left bars) and patient (right bars) PI (column one), AI (column two), cell density (column three), and viable rim thickness (column four) for our original calibration method (left blue bars) and the improved calibration (middle black bars), from T150 to 45 days in our simulations. While the original calibration (left blue bars) was consistent with the patient data (right red bars), the new calibration (middle black bars) gives simulated means that match the patient data much more closely. (For interpretation of the references to color in this figure caption, the reader is referred to the web version of this article.)
See this image and copyright information in PMC

Comment on

References

    1. Macklin P, Edgerton ME, Thompson AM, Cristini V, 2012. Patient-calibrated agent-based modelling of ductal carcinoma in situ (DCIS): from microscopic measurements to macroscopic predictions of clinical progression. J. Theor. Biol 301, 122–140, 10.1016/j.jtbi.2012.02.002. - DOI - PMC - PubMed
    1. Mumenthaler S, Hyun A, Macklin P Integrative experimental–computational modeling of intracellular water transport and solid synthesis in breast cancer cells: implications for patient-specific simulation of ductal carcinoma in situ (DCIS). Phys. Biol, in preparation.