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Review
. 2012 Nov 12;51(46):11426-37.
doi: 10.1002/anie.201204687. Epub 2012 Oct 19.

18F labeling of arenes

Matthew Tredwell  1 , Véronique Gouverneur
Affiliations
Review

18F labeling of arenes

Matthew Tredwell et al. Angew Chem Int Ed Engl. .

Abstract

Molecular imaging has witnessed an upsurge in growth, with positron emission tomography leading the way. This trend has encouraged numerous synthetic chemists to enter the field of (18) F-radiochemistry and provide generic solutions to address the well-recognized challenges of late-stage fluorination. This Minireview focuses on recent developments in the (18)F-labeling of aromatic substrates.

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