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Review
. 2012:2012:959061.
doi: 10.1155/2012/959061. Epub 2012 Oct 10.

Novel therapeutic/integrative approaches for celiac disease and dermatitis herpetiformis

Alessio Fasano  1
Affiliations
Review

Novel therapeutic/integrative approaches for celiac disease and dermatitis herpetiformis

Alessio Fasano. Clin Dev Immunol. 2012.

Abstract

Celiac disease (CD) is an immune-mediated enteropathy triggered by the ingestion of gluten in genetically susceptible individuals. Gluten is a protein component in wheat and other cereals like rye and barley. At present, the only available treatment is a strict gluten-free diet. Recent advances have increased our understanding of the molecular basis for this disorder. Last decade has seen new scientific developments in this disease and led to the formulation of new concepts of pathophysiology that offer possible targets for new treatments or interventions integrative to the gluten-free diet.

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Figures

Figure 1
Figure 1
Schematic representation of intestinal mucosal events involved in celiac disease pathogenesis.
Figure 2
Figure 2
Current clinical trials in celiac disease involving preventive and therapeutic interventions. Data obtained from http://www.clinicaltrials.gov/ update to July 10th 2012.
See this image and copyright information in PMC

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