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Review
. 2013 Feb;106(2):105-15.
doi: 10.1093/qjmed/hcs187. Epub 2012 Oct 24.

A critical overview on ticagrelor in acute coronary syndromes

E P Navarese  1 , A Buffon, M Kozinski, K Obonska, M Rychter, V Kunadian, D Austin, S De Servi, A Sukiennik, J Kubica
Affiliations
Review

A critical overview on ticagrelor in acute coronary syndromes

E P Navarese et al. QJM. 2013 Feb.

Abstract

Until a few years ago, the mainstay of anti-platelet therapy in patients with acute coronary syndrome (ACS) was the combination of aspirin and clopidogrel, a P2Y12 receptor inhibitor. However, current clinical practice has now changed with the introduction of ticagrelor, a more potent cardiovascular drug than clopidogrel, without the limitations related to clopidogrel therapy. In this review, we provide a critical overview of ticagrelor in ACS, highlight the results with ticagrelor in several subgroups of patients and discuss the future trials.

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