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Review
. 2012 Sep-Oct;109(5):371-5.

Acute respiratory distress syndrome

Ashley Mann  1 , Gerald L Early
Affiliations
Review

Acute respiratory distress syndrome

Ashley Mann et al. Mo Med. 2012 Sep-Oct.

Abstract

Acute Respiratory Distress Syndrome (ARDS) is defined by bilateral diffuse infiltrates on chest radiography, a PO2/FiO2 ratio < 200, and noncardiogenic pulmonary edema. Pathophysiologically it is characterized by disruption of the alveolar lining and capillary endothelium, alveolar edema, protein exudation coupled with a marked inflammatory response and subsequent fibrosis and a resultant ventilation-perfusion mismatch. Effective treatment strategies include low tidal volume ventilation with positive end expiratory pressure, careful fluid management and good supportive care.

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Figure 1
Chest X-ray in ARDS
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