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doi: 10.1016/j.cub.2012.08.003.
Circadian rhythms: An electric jolt to the clock
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- PMID: 23098596
- DOI: 10.1016/j.cub.2012.08.003
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Circadian rhythms: An electric jolt to the clock
Curr Biol.
.
Free article
Abstract
The animal circadian pacemaker is composed of two transcriptional feedback loops, which regulate electrical activity in circadian neurons. Surprisingly, a new study reports that electrical activity can reprogram circadian transcription, and identifies CREB proteins as candidates for this reprograming.
Copyright © 2012 Elsevier Ltd. All rights reserved.
Comment on
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Electrical activity can impose time of day on the circadian transcriptome of pacemaker neurons.Curr Biol. 2012 Oct 23;22(20):1871-80. doi: 10.1016/j.cub.2012.07.070. Epub 2012 Aug 30. Curr Biol. 2012. PMID: 22940468 Free PMC article.
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