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Comment
. 2012 Oct 23;22(20):R876-8.
doi: 10.1016/j.cub.2012.08.003.

Circadian rhythms: An electric jolt to the clock

Patrick Emery  1
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Free article
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Circadian rhythms: An electric jolt to the clock

Patrick Emery. Curr Biol. .
Free article

Abstract

The animal circadian pacemaker is composed of two transcriptional feedback loops, which regulate electrical activity in circadian neurons. Surprisingly, a new study reports that electrical activity can reprogram circadian transcription, and identifies CREB proteins as candidates for this reprograming.

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