Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2008 Jun;48(2):163-72.
doi: 10.1007/s12088-008-0030-5. Epub 2008 Jul 27.

A biological treasure metagenome: pave a way for big science

So-Youn Park  1 , Geun-Joong Kim
Affiliations

A biological treasure metagenome: pave a way for big science

So-Youn Park et al. Indian J Microbiol. 2008 Jun.

Abstract

The trend of recent researches, in which synthetic biology and white technology through system approaches based on "Omics technology" are recognized as the ground of biotechnology, indicates the coming of the 'metagenome era' that accesses the genomes of all microbes aiming at the understanding and industrial application of the whole microbial resources. The remarkable advance of technologies for digging out and analyzing metagenome is enabling not only practical applications of metagenome but also system approaches on a mixed-genome level based on accumulated information. In this situation, the present review is purposed to introduce the trends and methods of research on metagenome and to examine big science led by related resources in the future.

Keywords: Biological treasure; Gene mining; Metagenome; Novel metabolites; Systems approach.

PubMed Disclaimer

Similar articles

See all similar articles

Cited by

References

    1. Hunter-Cevera J.C. The value of microbial diversity. Curr Opin Microbiol. 1998;1:278–285. doi: 10.1016/S1369-5274(98)80030-1. - DOI - PubMed
    1. Eisen J.A. Environmental shotgun sequencing: its potential and challenges for studying the hidden world of microbes. PLoS Biol. 2007;5:e82. doi: 10.1371/journal.pbio.0050082. - DOI - PMC - PubMed
    1. Zwolinski M.D. DNA sequencing: Strategies for soil microbiology. Soil Sci Am J. 2007;71:592–600. doi: 10.2136/sssaj2006.0125. - DOI
    1. Handelsman J. Metagenomics: application of genomics to uncultured microorganisms. Microbiol Mol Biol Rev. 2004;68:669–685. doi: 10.1128/MMBR.68.4.669-685.2004. - DOI - PMC - PubMed
    1. Bull A.T., Ward A.C., Goodfellow M. Search and discovery strategies for biotechnology: The paradigm shift. Microbiol Mol Biol Rev. 2000;64:573–606. doi: 10.1128/MMBR.64.3.573-606.2000. - DOI - PMC - PubMed

LinkOut - more resources