On the origin of influenza A hemagglutinin

doi:10.1007/s12088-009-0062-5

. 2009 Dec;49(4):352-7.

doi: 10.1007/s12088-009-0062-5. Epub 2010 Jan 7.

On the origin of influenza A hemagglutinin

Derek Gatherer¹

Affiliations

PMID: 23100797
PMCID: PMC3450198
DOI: 10.1007/s12088-009-0062-5

On the origin of influenza A hemagglutinin

Derek Gatherer. Indian J Microbiol. 2009 Dec.

. 2009 Dec;49(4):352-7.

doi: 10.1007/s12088-009-0062-5. Epub 2010 Jan 7.

Author

Derek Gatherer¹

Affiliation

¹ MRC Virology Unit, Institute of Virology, University of Glasgow, Church Street, Glasgow, G11 5JR UK.

PMID: 23100797
PMCID: PMC3450198
DOI: 10.1007/s12088-009-0062-5

Abstract

Recent advances in phylogenetic methods have produced some reassessments of the ages of the most recent common ancestor of hemagglutinin proteins in known strains of influenza A. This paper applies Bayesian phylogenetic analysis implemented in BEAST to date the nodes on the influenza A hemagglutinin tree. The most recent common ancestor (MRCA) of influenza A hemagglutinin proteins is located with 95% confidence between 517 and 1497 of the Common Era (AD), with the center of the probability distribution at 1056 AD. The implications of this revised dating for both historical and current epidemiology are discussed. Influenza A can be seen as an emerging disease of mediaeval and early modern times.

Keywords: H1N1; Hemagglutinin; Influenza A.

PubMed Disclaimer

Cited by

Unveiling the Antiviral Potential of Minocycline: Modulation of Nuclear Export of Viral Ribonuclear Proteins during Influenza Virus Infection.
Saha P, Saha R, Datta Chaudhuri R, Sarkar R, Sarkar M, Koley H, Chawla-Sarkar M. Saha P, et al. Viruses. 2024 Aug 18;16(8):1317. doi: 10.3390/v16081317. Viruses. 2024. PMID: 39205291 Free PMC article.

References

1. Altschuler E.L., Kariuki Y.M., Jobanputra A. Extant blood samples to deduce the strains of the 1890 and possibly earlier pandemic influenzas. Medi Hypotheses. 2009;73:846–848. doi: 10.1016/j.mehy.2009.04.019. - DOI - PubMed
1. Potter C.W. A history of influenza. J Appl Microbiol. 2001;91:572–579. doi: 10.1046/j.1365-2672.2001.01492.x. - DOI - PubMed
1. Fraser C., Donnelly C.A., Cauchemez S., Hanage W.P., Kerkhove M.D., Hollingsworth T.D., Griffin J., Baggaley R.F., Jenkins H.E., Lyons E.J., Jombart T., Hinsley W.R., Grassly N.C., Balloux F., Ghani A.C., Ferguson N.M., Rambaut A., Pybus O.G., Lopez-Gatell H., Alpuche-Aranda C.M., Chapela I.B., Zavala E.P., Guevara D.M., Checchi F., Garcia E., Hugonnet S., Roth C. Pandemic potential of a strain of influenza A (H1N1): early findings. Science. 2009;324:1557–1561. doi: 10.1126/science.1176062. - DOI - PMC - PubMed
1. Dawood F.S., Jain S., Finelli L., Shaw M.W., Lindstrom S., Garten R.J., Gubareva L.V., Xu X., Bridges C.B., Uyeki T.M. Emergence of a novel swine-origin influenza A (H1N1) virus in humans. N Engl J Med. 2009;360:2605–2615. doi: 10.1056/NEJMoa0903810. - DOI - PubMed
1. Gatherer D. The 2009 H1N1 influenza outbreak in its historical context. J Clin Virol. 2009;45:174–178. doi: 10.1016/j.jcv.2009.06.004. - DOI - PubMed

LinkOut - more resources

Full Text Sources
- Europe PubMed Central
- PubMed Central
Other Literature Sources
- The Lens - Patent Citations Database

[1] Altschuler E.L., Kariuki Y.M., Jobanputra A. Extant blood samples to deduce the strains of the 1890 and possibly earlier pandemic influenzas. Medi Hypotheses. 2009;73:846–848. doi: 10.1016/j.mehy.2009.04.019. - DOI - PubMed

[2] Altschuler E.L., Kariuki Y.M., Jobanputra A. Extant blood samples to deduce the strains of the 1890 and possibly earlier pandemic influenzas. Medi Hypotheses. 2009;73:846–848. doi: 10.1016/j.mehy.2009.04.019. - DOI - PubMed

[3] Potter C.W. A history of influenza. J Appl Microbiol. 2001;91:572–579. doi: 10.1046/j.1365-2672.2001.01492.x. - DOI - PubMed

[4] Potter C.W. A history of influenza. J Appl Microbiol. 2001;91:572–579. doi: 10.1046/j.1365-2672.2001.01492.x. - DOI - PubMed

[5] Fraser C., Donnelly C.A., Cauchemez S., Hanage W.P., Kerkhove M.D., Hollingsworth T.D., Griffin J., Baggaley R.F., Jenkins H.E., Lyons E.J., Jombart T., Hinsley W.R., Grassly N.C., Balloux F., Ghani A.C., Ferguson N.M., Rambaut A., Pybus O.G., Lopez-Gatell H., Alpuche-Aranda C.M., Chapela I.B., Zavala E.P., Guevara D.M., Checchi F., Garcia E., Hugonnet S., Roth C. Pandemic potential of a strain of influenza A (H1N1): early findings. Science. 2009;324:1557–1561. doi: 10.1126/science.1176062. - DOI - PMC - PubMed

[6] Fraser C., Donnelly C.A., Cauchemez S., Hanage W.P., Kerkhove M.D., Hollingsworth T.D., Griffin J., Baggaley R.F., Jenkins H.E., Lyons E.J., Jombart T., Hinsley W.R., Grassly N.C., Balloux F., Ghani A.C., Ferguson N.M., Rambaut A., Pybus O.G., Lopez-Gatell H., Alpuche-Aranda C.M., Chapela I.B., Zavala E.P., Guevara D.M., Checchi F., Garcia E., Hugonnet S., Roth C. Pandemic potential of a strain of influenza A (H1N1): early findings. Science. 2009;324:1557–1561. doi: 10.1126/science.1176062. - DOI - PMC - PubMed

[7] Dawood F.S., Jain S., Finelli L., Shaw M.W., Lindstrom S., Garten R.J., Gubareva L.V., Xu X., Bridges C.B., Uyeki T.M. Emergence of a novel swine-origin influenza A (H1N1) virus in humans. N Engl J Med. 2009;360:2605–2615. doi: 10.1056/NEJMoa0903810. - DOI - PubMed

[8] Dawood F.S., Jain S., Finelli L., Shaw M.W., Lindstrom S., Garten R.J., Gubareva L.V., Xu X., Bridges C.B., Uyeki T.M. Emergence of a novel swine-origin influenza A (H1N1) virus in humans. N Engl J Med. 2009;360:2605–2615. doi: 10.1056/NEJMoa0903810. - DOI - PubMed

[9] Gatherer D. The 2009 H1N1 influenza outbreak in its historical context. J Clin Virol. 2009;45:174–178. doi: 10.1016/j.jcv.2009.06.004. - DOI - PubMed

[10] Gatherer D. The 2009 H1N1 influenza outbreak in its historical context. J Clin Virol. 2009;45:174–178. doi: 10.1016/j.jcv.2009.06.004. - DOI - PubMed

Save citation to file

Email citation

Add to Collections

Add to My Bibliography

Your saved search

Create a file for external citation management software

Your RSS Feed

On the origin of influenza A hemagglutinin

Affiliation

On the origin of influenza A hemagglutinin

Author

Affiliation

Abstract

Similar articles

Cited by

References

LinkOut - more resources

Full Text Sources

Other Literature Sources