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Comment
. 2012 Nov;44(11):1176-7.
doi: 10.1038/ng.2449.

FOXA1 and breast cancer risk

Kerstin B Meyer  1 , Jason S Carroll
Affiliations
Comment

FOXA1 and breast cancer risk

Kerstin B Meyer et al. Nat Genet. 2012 Nov.

Abstract

Many SNPs associated with human disease are located in non-coding regions of the genome. A new study shows that SNPs associated with breast cancer risk are located in enhancer regions and alter binding affinity for the pioneer factor FOXA1.

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References

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