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Editorial
. 2012 Oct 26;111(10):1250-2.
doi: 10.1161/CIRCRESAHA.112.279398.

Returns of the living dead: therapeutic action of irradiated and mitotically inactivated embryonic stem cells

Editorial

Returns of the living dead: therapeutic action of irradiated and mitotically inactivated embryonic stem cells

Joseph D Gold et al. Circ Res. .
No abstract available

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Figures

Figure 1
Figure 1
Potential mechanisms of action of injected cells for treatment of acute myocardial infarction: direct replacement of dead cardiomyocytes; structural reinforcement of the damaged ventricle by noncontracting but healthy cells that preserves normal heart geometry; converting hibernating myocardium back to contractile tissue; stimulation of regeneration from endogenous cells (whether cardiac-resident or extracardiac); limiting scar formation by induction of immunomodulatory cytokines as the host responds to the presence of apoptotic cells.

Comment on

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