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. 1990;247(1):37-9.
doi: 10.1007/BF00240947.

The effect of taurine supplementation on the ototoxicity of neomycin in guinea pigs

I S Kay  1 , W E Davies
Affiliations

The effect of taurine supplementation on the ototoxicity of neomycin in guinea pigs

I S Kay et al. Eur Arch Otorhinolaryngol. 1990.

Abstract

Experiments have been performed to examine the effects of taurine supplementation on the ototoxicity of neomycin. It was found that concurrent administration of taurine and neomycin produced a greater degree of ototoxicity, as evidenced by increases in hearing thresholds, than with neomycin alone. The results are discussed in light of a recently proposed mechanism of aminoglycoside ototoxicity.

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References

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