Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2012 Mar 1;1(1):1-8.
doi: 10.1007/s13679-011-0001-8.

Gut Microbiota and Obesity

Kyle J Wolf  1 , Robin G Lorenz
Affiliations

Gut Microbiota and Obesity

Kyle J Wolf et al. Curr Obes Rep. .

Abstract

The current obesity epidemic clearly has many causes, including the impact of our modern world on both our diet and our lifestyle/physical activity. Although many interventions have been recommended, the prevalence of obesity continues to rise and has forced a re-evaluation of the potential interventions that could have an impact. In recent years it has been definitively shown that microbiota in the gastrointestinal tract are altered in obese individuals. Recent data provide a potential mechanistic understanding of the interactions between microbiota and obesity and allow potential new interventions to the control of obesity to be proposed.

PubMed Disclaimer

Conflict of interest statement

Disclosure

No potential conflicts of interest relevant to this article were reported.

References

    1. Flegal KM, Carroll MD, Ogden CL, Curtin LR. Prevalence and trends in obesity among US adults, 1999–2008. JAMA : the journal of the American Medical Association. 2010;303(3):235–241. - PubMed
    1. James WP. The fundamental drivers of the obesity epidemic. Obes Rev. 2008;9(Suppl 1):6–13. - PubMed
    1. Bäckhed F, Ding H, Wang T, Hooper LV, Koh GY, Nagy A, et al. The gut microbiota as an environmental factor that regulates fat storage. Proceedings of the National Academy of Sciences of the United States of America. 2004;101(44):15718–15723. PMCID: 524219. - PMC - PubMed
    1. Shanahan F. The host-microbe interface within the gut. Best practice & research Clinical gastroenterology. 2002;16(6):915–931. - PubMed
    1. Turnbaugh PJ, Ridaura VK, Faith JJ, Rey FE, Knight R, Gordon JI. The effect of diet on the human gut microbiome: a metagenomic analysis in humanized gnotobiotic mice. Sci Transl Med. 2009;1(6):6ra14. PMCID: 2894525. - PMC - PubMed

LinkOut - more resources