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Case Reports
. 1979 Jul-Sep;2(3):267-70.
doi: 10.1007/BF03350414.

Influence of magnesium on the secretion and action of parathyroid hormone

K S Nair, I M Holdaway, M C Evans, A D Cameron
Case Reports

Influence of magnesium on the secretion and action of parathyroid hormone

K S Nair et al. J Endocrinol Invest. 1979 Jul-Sep.

Abstract

The interactions of serum levels of magnesium and parathyroid hormone (PTH) have been studied in a patient with hypomagnesemia and hypocalcemia following intestinal bypass surgery for obesity. When serum magnesium was low serum PTH was not stimulated by hypocalcemia. With correction of magnesium deficiency hypocalcemia was associated with elevation of serum PTH levels. Infusion of exogenous PTH induced a clearly detectable renal response in the presence of hypomagnesemia but the response was diminished when serum magnesium was elevated. In this patient it appears that hypomagnesemia suppressed parathyroid gland activity, leaving the renal action of PTH intact.

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References

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