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. 2013 Feb;131(2):587-90.e1-3.
doi: 10.1016/j.jaci.2012.08.040. Epub 2012 Oct 26.

Aberrant glycosylation of IgA in Wiskott-Aldrich syndrome and X-linked thrombocytopenia

Masaki Shimizu, Hirokazu Kanegane, Taizo Wada, Yaeko Motoyoshi, Tomohiro Morio, Fabio Candotti, Akihiro Yachie

Aberrant glycosylation of IgA in Wiskott-Aldrich syndrome and X-linked thrombocytopenia

Masaki Shimizu et al. J Allergy Clin Immunol. 2013 Feb.
No abstract available

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Conflict of interest statement

Disclosure

The authors have no financial conflicts of interest to disclose.

Figures

Figure 1
Figure 1. Increased serum galactose-deficient IgA levels and CIC containing IgA and IgG in WAS/XLT
The bars represent the median values. Open triangles, XLT; filled squares, WAS. A. Serum levels of galactose-deficient IgA B,C. Correlation between serum galactose-deficient IgA levels and age. D. Serum levels of IgG-IgA CIC E,F. The correlation between serum levels of IgG-IgA CIC and age.
Figure 2
Figure 2. Improved XLT-associated IgAN and decreased the production of aberrant IgA after BMT
A, B: Immunofluorescence (IF) studies of kidney biopsy specimens from patient 16. C: Changes of the levels of galactose-deficient IgA after BMT
See this image and copyright information in PMC

References

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