Does previous varicose vein surgery alter deep vein thrombosis risk after lower limb arthroplasty?
- PMID: 23109306
- PMCID: PMC6583367
- DOI: 10.1111/os.12003
Does previous varicose vein surgery alter deep vein thrombosis risk after lower limb arthroplasty?
Abstract
Objective: To determine the rates of deep vein thrombosis (DVT) and pulmonary embolism (PE) after total knee arthroplasty (TKA) and total hip arthroplasty (THA) in patients who have had previous varicose vein (VV) surgery.
Methods: Data on 57,364 patients who had undergone THAs and 51,859 patients who had undergone TKAs were obtained from the Scottish Arthroplasty Project and cross-referenced with patients for whom DVT/PE events had been recorded (Scottish Morbidity Database).
Results: The THA DVT rate in patients who had previously undergone VV surgery was 0.8% (27/3478), and in those with no previous VV diagnosis or surgery was 0.8% (428/53,659). In patients with a previous VV diagnosis but no VV surgery, the THA DVT rate was 3.1% (7/227) (Pearson χ2 test, χ2 = 14.8, degrees of freedom = 2, P = 0.001). No significant difference was found for the corresponding data in the TKA cohort. The THA PE rate in patients who had previously undergone VV surgery was 0.7% (26/3478), and in those with no previous VV diagnosis or surgery 0.7% (376/53,659). No correlation was found between prior VV interventions and PE rates.
Conclusion: Untreated VVs are associated with an increased risk of DVT after THA. Therefore, patients with VVs should consider having them treated prior to undergoing orthopedic interventions.
© 2012 Tianjin Hospital and Wiley Publishing Asia Pty Ltd.
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References
-
- Silverstein MD, Heit JA, Mohr DN, et al Trends in the incidence of deep vein thrombosis and pulmonary embolism: a 25‐year population‐based study. Arch Intern Med, 1998, 158: 585–593. - PubMed
-
- Anderson FA Jr, Wheeler HB, Goldberg RJ, et al A population‐based perspective of the hospital incidence and case‐fatality rates of deep vein thrombosis and pulmonary embolism. The Worcester DVT Study. Arch Intern Med, 1991, 151: 933–938. - PubMed
-
- Xing KH, Morrison G, Lim W, et al Has the incidence of deep vein thrombosis in patients undergoing total hip/knee arthroplasty changed over time? A systematic review of randomized controlled trials. Thromb Res, 2008, 123: 24–34. - PubMed
-
- Schindler OS, Dalziel R. Post‐thrombotic syndrome after total hip or knee arthroplasty: incidence in patients with asymptomatic deep venous thrombosis. J Orthop Surg (Hong Kong), 2005, 13: 113–119. - PubMed
-
- Rossman I, Rodstein M, Bornstein A. Undiagnosed diseases in an aging population. Pulmonary embolism and bronchopneumonia. Arch Intern Med, 1974, 133: 366–369. - PubMed
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