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Comment
. 2012 Nov;5(6):709-10.
doi: 10.1242/dmm.010876.

Finding NECA: zebrafish screen identifies key signalling pathway in β-cell regeneration

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Comment

Finding NECA: zebrafish screen identifies key signalling pathway in β-cell regeneration

Asha Seth. Dis Model Mech. 2012 Nov.

Abstract

Summary of and comment on a recent Cell Metabolism paper entitled ‘Adenosine signaling promotes regeneration of pancreatic β cells in vivo’ (Andersson et al., 2012).

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References

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    1. Annes J. P., Ryu J. H., Lam K., Carolan P. J., Utz K., Hollister-Lock J., Arvanites A. C., Rubin L. L., Weir G., Melton D. A. (2012). Adenosine kinase inhibition selectively promotes rodent and porcine islet β-cell replication. Proc. Natl. Acad. Sci. USA 109, 3915–3920 - PMC - PubMed
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    1. Dor Y., Brown J., Martinez O. I., Melton D. A. (2004). Adult pancreatic beta-cells are formed by self-duplication rather than stem-cell differentiation. Nature 429, 41–46 - PubMed

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