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Comment
. 2012 Nov;5(6):711-2.
doi: 10.1242/dmm.010892.

Lactate-starved neurons in ALS

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Comment

Lactate-starved neurons in ALS

Bryan A Martinez. Dis Model Mech. 2012 Nov.

Abstract

Summary and comment on a recent Nature article entitled ‘Oligodendroglia metabolically support axons and contribute to neurodegeneration’ (Lee et al., 2012).

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References

    1. Allegretta M., Nicklas J. A., Sriram S., Albertini R. J. (1990). T cells responsive to myelin basic protein in patients with multiple sclerosis. Science 247, 718–721 - PubMed
    1. Baumann N., Pham-Dinh D. (2001). Biology of oligodendrocyte and myelin in the mammalian central nervous system. Physiol. Rev. 81, 871–927 - PubMed
    1. Chih C. P., Lipton P., Roberts E. L., Jr (2001). Do active cerebral neurons really use lactate rather than glucose? Trends Neurosci. 24, 573–578 - PubMed
    1. Draoui N., Feron O. (2011). Lactate shuttles at a glance: from physiological paradigms to anti-cancer treatments Dis. Model. Mech. 4, 727–732 - PMC - PubMed
    1. Garbern J. Y., Yool D. A., Moore G. J., Wilds I. B., Faulk M. W., Klugmann M., Nave K. A., Sistermans E. A., van der Knaap M. S., Bird T. D., et al. (2002). Patients lacking the major CNS myelin protein, proteolipid protein 1, develop length-dependent axonal degeneration in the absence of demyelination and inflammation. Brain 125, 551–561 - PubMed

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