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. 2013 Jan;51(1):299-302.
doi: 10.1128/JCM.01196-12. Epub 2012 Oct 31.

Population dynamics of tuberculous Bacilli in Cameroon as assessed by spoligotyping

Francioli Koro Koro  1 , Yannick Kamdem Simo, Félix Fotso Piam, Jurgen Noeske, Cristina Gutierrez, Christopher Kuaban, Sara Irène Eyangoh
Affiliations

Population dynamics of tuberculous Bacilli in Cameroon as assessed by spoligotyping

Francioli Koro Koro et al. J Clin Microbiol. 2013 Jan.

Abstract

Genetic assessment by spoligotyping of 565 Mycobacterium tuberculosis complex strains collected from the Western Region of Cameroon between 2004 and 2005 has confirmed the establishment of the "Cameroon family" as the leading cause of tuberculosis in 45.9% of cases and evidenced the rapid quasi extinction of Mycobacterium africanum, isolated in 3.3% of tuberculosis cases.

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Figures

Fig 1
Fig 1
Dendrogram and schematic representation of 94 spoligotypes identified from 565 M. tuberculosis complex strains isolated from positive pulmonary tuberculosis patients from West Cameroon. The degree of similarity of spoligotypes was calculated with the 1-Jaccard index, and the relationships between patterns were assessed by the unweighted-pair group method using average linkages. The spoligotype code, the shared international type (SIT), and lineage are listed. ND, not determined. CAM, Cameroonian spoligotype corresponding to a strain isolated in this study.
Fig 2
Fig 2
Histogram showing the 7-year evolution of the MTBC population in West Cameroon.
See this image and copyright information in PMC

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