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Case Reports
. 2012 Sep;52(3):261-3.
doi: 10.3340/jkns.2012.52.3.261. Epub 2012 Sep 30.

Deep Brain Stimulation of the Globus Pallidus in a 7-Year-Old Girl with DYT1 Generalized Dystonia

Seon Tak Jin  1 , Myung Ki Lee, Ju Young Ghang, Seong Man Jeon
Affiliations
Case Reports

Deep Brain Stimulation of the Globus Pallidus in a 7-Year-Old Girl with DYT1 Generalized Dystonia

Seon Tak Jin et al. J Korean Neurosurg Soc. 2012 Sep.

Abstract

The experience of pediatric deep brain stimulation (DBS) of the globus pallidus internus (GPi) in the treatment of early-onset DYT1 generalized dystonia is still limited. Here, we report the surgical experience of bilateral GPi-DBS under general anesthesia by using microelectrode recording in a 7-year-old girl with early-onset DYT1 generalized dystonia. Excellent improvement of her dystonia without neurological complications was achieved. This case report demonstrates that GPi-DBS is an effective and safe method for the treatment of medically refractory early-onset DYT1 generalized dystonia in children.

Keywords: DYT1; Deep brain stimulation; Dystonia; Globus pallidus.

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Figures

Fig. 1
Fig. 1
Postoperative MRI axial T2-weighted (A) and coronal T2-weighted (B) images showing the electrodes within the posteroventral globus pallidus internus.
Fig. 2
Fig. 2
Preoperative photography of patient showing clinical feature of generalized dystonia (A). Photography of 1 month after surgery shows maintaining of an erect standing position (B).
Fig. 3
Fig. 3
Preoperative (A) and postoperative (B) photography of patient's hand drawing and writing.
See this image and copyright information in PMC

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