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. 2006 Jan;58(1):31-4.
doi: 10.1007/BF02907735.

Supravital staining: It's role in detecting early malignancies

Mahesh Chandra Hedge  1 , Panduranga M Kamath, Suja Shreedharan, Naveen Kumar Dannana, Ravikumar M Raju
Affiliations

Supravital staining: It's role in detecting early malignancies

Mahesh Chandra Hedge et al. Indian J Otolaryngol Head Neck Surg. 2006 Jan.

Abstract

The efficacy of supravital staining in the detection of malignancies in oro and oropharyngeal lesions and its role in the detection of malignant changes in premalignant lesions were studied. This prospective study comprises 90 cases of clinically suspicious lesions and it was done over a period of 3 years. Most of the patients had multiple risk factors for the development of malignancy. All underwent staining with a modified solution of 1% toluidine blue (TB). In our study the overall sensitivity was 97.29% and the specificity was 62.5%.

Keywords: Supravital staining; cancer detection; oral and oropharyngeal malignancy; premalignant conditions; toluidine blue.

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