Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2006 Jul;58(3):246-8.
doi: 10.1007/BF03050831.

FNAC of salivary gland lesions with histopathological correlation

M M Khandekar  1 , A N Kavatkar, S A Patankar, I B Bagwan, S C Puranik, S D Deshmukh
Affiliations

FNAC of salivary gland lesions with histopathological correlation

M M Khandekar et al. Indian J Otolaryngol Head Neck Surg. 2006 Jul.

Abstract

Hypothesis: Analysis of salivary gland lesions by FNAC and correlation with histopathology. To evaluate utility of FNAC in salivary gland lesions.Back ground: Salivary gland lesions form about 2-6.5% of all head and neck neoplasms in adults. They are easily accessible for FNAC (Fine Needle Aspiration Cytology) and risks of fistula formation or tumour implantation are low compared surgical biopsy. Also, cytology can provide a distinction between asalivary and non salivary lesion, benign and malignant lesions so also specific and non specific inflammation.

Methods: Seventy patients were studied prospectively over two years. FNAC was done using 10 cc syringes and 20-22 no. needle. Histomorphology was assessed on routine H & E (haemotxylin and eosin) stained paraffin sections. SPAS (periodic acid Schiff) and mucicarmine satins were also done.

Results: 80% of the lesions were neoplastic (61% benign, 31% malignant) and 20% were neoplastic. Pleomorphic adenoma was the most frequent benign neoplasm while mucoepidermoid carcinoma was the most frequent malignant lesion. Among the non neoplastic lesions, the maximum number of cases were of chronic sialadentis. In the present study, FNAC has a sensitivity of 94.54% and specificity of 80.95% for neoplastic lesions.

Conclusions: FNAC was found to be a useful diagnostic tool in the evaluation of salivary gland lesions because of its simplicity, excellent patient compliance and rapid diagnosis. This cost effective tool is invaluable in planning the surgical management of the patient.

Keywords: FNAC; Salivary Gland; Salivary Gland Tumours.

PubMed Disclaimer

References

    1. Auclair P.L., Ellis G.L. Major Salivary Glands. In: Silverberg SG, Delellis R.A., Frable W.J., editors. Principles and Practice of Surgical Pathology and Cytopathology. 3rd. Edinburgh: Churchill Livingstone; 1997. pp. 1461–1515.
    1. Orell S, Max Strerett G.F., Walters N., Whitaker D. Manual and Atlas of the fine needle aspiration cytology. 3rd. Edinburgh: Churchill Livingstone; 1999. pp. 38–72.
    1. Sousa J, Oswald Sa. Salivary Gland tumors: an analysis of 62 cases. Ind J of Cancer. 2001;38:38–45. - PubMed
    1. Cristallinin EG, Ascani S. Fine Needle aspiration biopsy of salivary gland. Acta Cytol; 41(5): 1421–1425 - PubMed
    1. Chatterjee T, Panda P.K. Pathological study of benign and malignant tumours of salivary glands. MJAFI. 2000;56(4):282–286. - PMC - PubMed

LinkOut - more resources