Maps for changing landscapes: viewing epigenomic signatures through differentiation
- PMID: 23122282
- DOI: 10.1016/j.stem.2012.10.009
Maps for changing landscapes: viewing epigenomic signatures through differentiation
Abstract
Enormous progress has been made in identifying chromatin "signatures" that define tissue-specific transcriptional networks. Three recent studies by Rada-Iglesias et al. (2012), Wamstad et al. (2012), and Paige et al. (2012) track such signatures during cellular differentiation, revealing a richer understanding of gene regulation and providing hints of new phenomena.
Copyright © 2012 Elsevier Inc. All rights reserved.
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