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Randomized Controlled Trial
. 2014 Feb;37(1):70-80.
doi: 10.1007/s10865-012-9464-7.

Effects of guided imagery on biobehavioral factors in women with fibromyalgia

Affiliations
Randomized Controlled Trial

Effects of guided imagery on biobehavioral factors in women with fibromyalgia

Victoria Menzies et al. J Behav Med. 2014 Feb.

Abstract

Women diagnosed with fibromyalgia (N = 72) participated in a 10-week randomized trial to examine the effectiveness of guided imagery on self-efficacy, perceived stress, and selected biobehavioral factors (FMS symptoms; immune biomarkers). Participants in both guided imagery and usual care control conditions completed measures and donated 3 cc of blood at baseline, 6- and 10-weeks. A mixed effects linear model to test for differences between groups for all behavioral and biologic variables demonstrated that after 10 weeks of daily intervention use, guided imagery participants reported statistically significant increases in self-efficacy and statistically significant decreases in stress, fatigue, pain, and depression. There were no statistically significant changes in biomarker levels, although total group C-reactive protein was elevated at baseline (4.7 mg/L), indicating an inflammatory process. Subsequent studies should be undertaken to more fully elucidate the biobehavioral aspects of nonpharmacological intervention effectiveness.

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Figures

Figure 1
Figure 1
Conceptual Framework: Effects of Guided Imagery on Biobehavioral Factors in Women with Fibromyalgia
Figure 2
Figure 2
Flow Diagram of the Enrollment and Randomization of Women Diagnosed with Fibromyalgia* *Schulz, K. F., Altman, D. G., Moher, D., for the CONSORT Group. (2010). CONSORT 2010 statement: Updated guidelines for reporting parallel group randomised trials. British Medical Journal, 340, c. 322.

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