Anti-PreS2 antibody assay for evaluating immune responses among recipients of recombinant hepatitis B PreS2 + S vaccine
- PMID: 2313274
- DOI: 10.1002/jmv.1890300213
Anti-PreS2 antibody assay for evaluating immune responses among recipients of recombinant hepatitis B PreS2 + S vaccine
Abstract
A competitive radioimmunoassay was developed for measuring hepatitis B virus (HBV) anti-PreS2 antibody. The assay has been demonstrated to be highly specific for anti-PreS2 antibody and not subject to interference by other antibodies to HBV-specific antigens. This assay was used to evaluate anti-PreS2 antibody responses in a hepatitis B PreS2 + S vaccine human clinical trial in healthy adults.
Similar articles
-
Protective effect of a synthetic peptide comprising the complete preS2 region of the hepatitis B virus surface protein.J Med Virol. 1989 May;28(1):7-12. doi: 10.1002/jmv.1890280103. J Med Virol. 1989. PMID: 2723618
-
Hepatitis B virus core-preS2 particles expressed by recombinant vaccinia virus.Acta Virol. 1996 Nov-Dec;40(5-6):273-9. Acta Virol. 1996. PMID: 9171455
-
In vitro T cell immune responses to the preS2 antigen of the hepatitis B virus envelope protein in preS2 + S vaccine recipients. Absence of cross-reactivity of subtypes at a major T cell recognition site.J Immunol. 1993 Sep 15;151(6):3353-60. J Immunol. 1993. PMID: 7690803
-
The application of molecular biology to the development of novel vaccines.Adv Exp Med Biol. 1989;251:83-98. doi: 10.1007/978-1-4757-2046-4_7. Adv Exp Med Biol. 1989. PMID: 2532858 Review.
-
Interactions of hepatitis B virus with hepatocytes: mechanism and clinical relevance.Hepatogastroenterology. 1991 Feb;38(1):10-3. Hepatogastroenterology. 1991. PMID: 1709133 Review.
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Medical