Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2009 Apr;71(2):73-7.
doi: 10.1007/s12262-009-0020-9. Epub 2009 May 2.

The effect of Kombucha on post-operative intra-abdominal adhesion formation in rats

Hemmat Maghsoudi  1 , Hussein Benagozar Mohammadi
Affiliations

The effect of Kombucha on post-operative intra-abdominal adhesion formation in rats

Hemmat Maghsoudi et al. Indian J Surg. 2009 Apr.

Abstract

Background: Peritoneal adhesions are fibrous bands of tissues formed between organs that are normally separated and/or between organs and the internal body wall after peritoneal injury. The aim of the study was to investigate the effect of intra-peritoneal administration of Kombucha on intra-peritoneal adhesions.

Materials and methods: Eighty Wistar rats were subjected to standardized lesion by scraping model and were randomly divided into two groups. Group I received no treatment, and Group II received 15 ml of Kombucha solution intra-peritoneally. On the post-operative 14th day adhesion intensity score, inflammatory cell reaction and number of adhesion bands were determined.

Results: In the control group, there were no rats with grade 0 and I adhesions. In the group II, there were 26 rats (78.8%) with grade 0-2 adhesions. Adhesion intensity was significantly less in group II (P<0.0001). Number of adhesion bands was significantly less in group II (P<0.001).

Conclusion: It was concluded that intra-peritoneal administration of Kombucha might be useful for preventing peritoneal adhesions.

Keywords: Kombucha; Peritoneal adhesions; Prevention.

PubMed Disclaimer

Similar articles

See all similar articles

Cited by

References

    1. Ellis H., Moran B., Thompson J. Adhesion related hospital readmissions after abdominal and pelvic surgery: a retrospective cohort study. Lancet. 1999;353:1476–1480. doi: 10.1016/S0140-6736(98)09337-4. - DOI - PubMed
    1. Cheong Y.C., Laird S.M., Li T.C., Shelton J.B., Ledger W.L., Cooke I.D. Peritoneal healing and adhesion formation/reformation. Hum Reprod. 2001;7(6):556–566. doi: 10.1093/humupd/7.6.556. - DOI - PubMed
    1. DiZerega G.S., Campeau J.D. Peritoneal repair and postsurgical adhesion formation. Hum Reprod Update. 2001;7(6):547–555. doi: 10.1093/humupd/7.6.547. - DOI - PubMed
    1. Milligan D.W., Raftery A.T. Observations on the pathogenesis of peritoneal adhesions: a fight and electron microscopically study. Br J Surg. 1974;61:274–280. doi: 10.1002/bjs.1800610406. - DOI - PubMed
    1. DiZerega GS. The peritoneum and its response to surgical injury. In: diZerega ZG, Malinak L, Diamond M, Linsky C, editors. Treatment of post-surgical adhesions. New York: Wiley Liss. pp 166–171

LinkOut - more resources