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. 2009 Apr;71(2):73-7.
doi: 10.1007/s12262-009-0020-9. Epub 2009 May 2.

The effect of Kombucha on post-operative intra-abdominal adhesion formation in rats

Hemmat Maghsoudi  1 , Hussein Benagozar Mohammadi
Affiliations

The effect of Kombucha on post-operative intra-abdominal adhesion formation in rats

Hemmat Maghsoudi et al. Indian J Surg. 2009 Apr.

Abstract

Background: Peritoneal adhesions are fibrous bands of tissues formed between organs that are normally separated and/or between organs and the internal body wall after peritoneal injury. The aim of the study was to investigate the effect of intra-peritoneal administration of Kombucha on intra-peritoneal adhesions.

Materials and methods: Eighty Wistar rats were subjected to standardized lesion by scraping model and were randomly divided into two groups. Group I received no treatment, and Group II received 15 ml of Kombucha solution intra-peritoneally. On the post-operative 14th day adhesion intensity score, inflammatory cell reaction and number of adhesion bands were determined.

Results: In the control group, there were no rats with grade 0 and I adhesions. In the group II, there were 26 rats (78.8%) with grade 0-2 adhesions. Adhesion intensity was significantly less in group II (P<0.0001). Number of adhesion bands was significantly less in group II (P<0.001).

Conclusion: It was concluded that intra-peritoneal administration of Kombucha might be useful for preventing peritoneal adhesions.

Keywords: Kombucha; Peritoneal adhesions; Prevention.

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