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. 2012:2012:165289.
doi: 10.1155/2012/165289. Epub 2012 Oct 24.

Nonmetastatic Ewing's Sarcoma of the Lumbar Spine in an Adult Patient

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Nonmetastatic Ewing's Sarcoma of the Lumbar Spine in an Adult Patient

Maurizio Iacoangeli et al. Case Rep Oncol Med. 2012.

Abstract

Although the spine is frequently involved in metastatic Ewing's sarcoma, primary involvement of the spine, beside sacrum, is much less frequent, especially in adult patients. Because of the low incidence of these tumors, there are currently no clinical guidelines outlining their management and a multitude of therapeutic strategies have been employed with varying success. The definitive management of Ewing's sarcoma of the spine, as in other locations, could include the combination of three main modalities: aggressive surgery, radiotherapy, and combined chemotherapy. Whenever possible, en bloc spondylectomy or extralesional resection is preferable, providing a better oncological result with a longer survival and a better preservation of the spine biomechanics. This is the lesson we learned about the case, we present here, of nonmetastatic lumbar localization by Ewing's sarcoma in as adult patient.

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Figures

Figure 1
Figure 1
Preoperative MRI images showing an enhancing mass occupying the left hemivertebra, pedicle, and hemilamina of L2.
Figure 2
Figure 2
Postoperative CT scan demonstrating the tumor removal and the anterior column reconstruction.
Figure 3
Figure 3
Histopathological images revealing the typical aspect of a densely cellular “blue tumor” composed of small round cells uniformly arranged in sheets and with strong membranous CD99 immunoreactivity (H&H stain ×20, CD99 immunohistochemical stain ×20).

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References

    1. Ellis JA, Rothrock RJ, Moise G, et al. Primitive neuroectodermal tumors of the spine: a comprehensive review with illustrative clinical cases. Neurosurgical Focus. 2011;30(1):1–13. - PubMed
    1. Venkateswaran L, Rodriguez-Galindo C, Merchant TE, Poquette CA, Rao BN, Pappo AS. Primary Ewing tumor of the vertebrae: clinical characteristics, prognostic factors, and outcome. Medical and Pediatric Oncology. 2001;37(1):30–35. - PubMed
    1. Rodriguez-Galindo C, Spunt SL, Pappo AS. Treatment of ewing sarcoma family of tumors: current status and outlook for the future. Medical and Pediatric Oncology. 2003;40(5):276–287. - PubMed
    1. Fizazi K, Dohollou N, Blay JY, et al. Ewing’s family of tumors in adults: multivariate analysis of survival and long-term results of multimodality therapy in 182 patients. Journal of Clinical Oncology. 1998;16(12):3736–3743. - PubMed
    1. Cotterill SJ, Ahrens S, Paulussen M, et al. Prognostic factors in Ewing’s tumor of bone: analysis of 975 patients from the European Intergroup Cooperative Ewing’s Sarcoma Study Group. Journal of Clinical Oncology. 2000;18(17):3108–3114. - PubMed