Chronic thromboembolic pulmonary hypertension: treat the patient not the haemodynamics
- PMID: 23133777
- PMCID: PMC3485485
- DOI: 10.1155/2012/108672
Chronic thromboembolic pulmonary hypertension: treat the patient not the haemodynamics
Abstract
Chronic thromboembolic pulmonary hypertension (CTEPH) is a disabling condition that is being increasingly recognised. It is unique as a cause of pulmonary hypertension in that it is surgically curable. We wish to highlight the importance of recognition and early referral of any patient who may have CTEPH even in the absence of resting pulmonary hypertension as excellent results can be achieved by restoring pulmonary vascular anatomy, reducing exercise-induced pulmonary hypertension, and reducing dead-space ventilation. We present a case that illustrates these points and discuss our experience as a referral centre for CTEPH.
Figures
Similar articles
-
Dead-space ventilation is linked to exercise capacity and survival in distal chronic thromboembolic pulmonary hypertension.J Heart Lung Transplant. 2017 Nov;36(11):1234-1242. doi: 10.1016/j.healun.2017.05.024. Epub 2017 May 22. J Heart Lung Transplant. 2017. PMID: 28666570
-
Inefficient exercise gas exchange identifies pulmonary hypertension in chronic thromboembolic obstruction following pulmonary embolism.Thromb Res. 2013;132(6):659-65. doi: 10.1016/j.thromres.2013.09.032. Epub 2013 Sep 27. Thromb Res. 2013. PMID: 24157082
-
Dual-energy CT (DECT) lung perfusion in pulmonary hypertension: concordance rate with V/Q scintigraphy in diagnosing chronic thromboembolic pulmonary hypertension (CTEPH).Eur Radiol. 2018 Dec;28(12):5100-5110. doi: 10.1007/s00330-018-5467-2. Epub 2018 May 30. Eur Radiol. 2018. PMID: 29846802
-
Recent progress in the diagnosis and management of chronic thromboembolic pulmonary hypertension.Respir Investig. 2013 Sep;51(3):134-46. doi: 10.1016/j.resinv.2013.02.005. Epub 2013 Apr 30. Respir Investig. 2013. PMID: 23978639 Review.
-
Chronic thromboembolic pulmonary hypertension.Presse Med. 2015 Dec;44(12 Pt 2):e409-16. doi: 10.1016/j.lpm.2015.10.010. Epub 2015 Nov 12. Presse Med. 2015. PMID: 26585271 Review.
References
-
- Lane DA, Bayston T, Olds RJ, et al. Antithrombin mutation database: 2nd update. For the Plasma Coagulation Inhibitors Subcommittee of the Scientific and Standardisation Committee of the International Society on Thrombosis and Haemostasis. Thrombosis and Haemostasis. 1997;77(1):197–211. - PubMed
-
- Pengo V, Lensing AWA, Prins MH, et al. Incidence of chronic thromboembolic pulmonary hypertension after pulmonary embolism. The New England Journal of Medicine. 2004;350(22):2257–2264. - PubMed
-
- Archibald CJ, Auger WR, Fedullo PF, et al. Long-term outcome after pulmonary thromboendarterectomy. American Journal of Respiratory and Critical Care Medicine. 1999;160(2):523–528. - PubMed
-
- Fowler RM, Maiorana AJ, Jenkins SC, Gain KR, O’Driscoll G, Gabbay E. Implications of exercise-induced pulmonary arterial hypertension. Medicine and Science in Sports and Exercise. 2011;43(6):983–989. - PubMed
-
- Jamieson SW, Kapelanski DP, Sakakibara N, et al. Pulmonary endarterectomy: experience and lessons learned in 1,500 cases. Annals of Thoracic Surgery. 2003;76(5):1457–1464. - PubMed
LinkOut - more resources
Full Text Sources