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Review
. 2012 Nov;53 Suppl 6(Suppl 6):45-52.
doi: 10.1111/j.1528-1167.2012.03702.x.

Inflammatory events at blood-brain barrier in neuroinflammatory and neurodegenerative disorders: implications for clinical disease

Helga E de Vries  1 , Gijs Kooij, Dan Frenkel, Spiros Georgopoulos, Alon Monsonego, Damir Janigro
Affiliations
Review

Inflammatory events at blood-brain barrier in neuroinflammatory and neurodegenerative disorders: implications for clinical disease

Helga E de Vries et al. Epilepsia. 2012 Nov.

Abstract

Proper function of the neurovasculature is required for optimal brain function and preventing neuroinflammation and neurodegeneration. Within this review, we discuss alterations of the function of the blood-brain barrier in neurologic disorders such as multiple sclerosis, epilepsy, and Alzheimer's disease and address potential underlying mechanisms.

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