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. 2013 Feb;51(2):595-7.
doi: 10.1128/JCM.02935-12. Epub 2012 Nov 7.

Colonization dynamics of antibiotic-resistant coagulase-negative Staphylococci in neonates

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Colonization dynamics of antibiotic-resistant coagulase-negative Staphylococci in neonates

Vishal Hira et al. J Clin Microbiol. 2013 Feb.

Abstract

Coagulase-negative staphylococci (CoNS) isolated in neonatal late-onset sepsis are often antibiotic resistant. We analyzed CoNS from skin and feces of neonates during hospitalization. Antibiotic resistance of skin isolates increased during hospitalization, especially in Staphylococcus haemolyticus. Staphylococcus warneri showed low antibiotic resistance. Our data suggest that different CoNS species may play distinct roles in colonization.

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Figures

Fig 1
Fig 1
Rates of resistant isolates for each tested antibiotic at different time points. Solid lines, neonatal skin isolates; dotted lines, neonatal intestine isolates; dashed lines, maternal isolates. Statistically significant differences are marked by asterisks for differences between skin and gut isolates, percent signs for differences between skin and maternal isolates, and dollar signs for differences between gut and maternal isolates.
Fig 2
Fig 2
Bacterial species distribution among study groups.

References

    1. Hira V, Sluijter M, Goessens WH, Ott A, de Groot R, Hermans PW, Kornelisse RF. 2010. Coagulase-negative staphylococcal skin carriage among neonatal intensive care unit personnel: from population to infection. J. Clin. Microbiol. 48:3876–3881 - PMC - PubMed
    1. Szewczyk EM, Piotrowski A, Rozalska M. 2000. Predominant staphylococci in the intensive care unit of a paediatric hospital. J. Hosp. Infect. 45:145–154 - PubMed
    1. Adlerberth I, Lindberg E, Aberg N, Hesselmar B, Saalman R, Strannegard IL, Wold AE. 2006. Reduced enterobacterial and increased staphylococcal colonization of the infantile bowel: an effect of hygienic lifestyle? Pediatr. Res. 59:96–101 - PubMed
    1. Wade JC, Schimpff SC, Newman KA, Wiernik PH. 1982. Staphylococcus epidermidis: an increasing cause of infection in patients with granulocytopenia. Ann. Intern. Med. 97:503–508s - PubMed
    1. Foka A, Chini V, Petinaki E, Kolonitsiou F, Anastassiou ED, Dimitracopoulos G, Spiliopoulou I. 2006. Clonality of slime-producing methicillin-resistant coagulase-negative staphylococci disseminated in the neonatal intensive care unit of a university hospital. Clin. Microbiol. Infect. 12:1230–1233 - PubMed