doi: 10.1007/978-1-62703-131-8_8.
The teratology testing of cosmetics
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- PMID: 23138898
- DOI: 10.1007/978-1-62703-131-8_8
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The teratology testing of cosmetics
Methods Mol Biol.
2013.
Abstract
In Europe, the developmental toxicity testing (including teratogenicity) of new cosmetic ingredients is performed according to the Cosmetics Directive 76/768/EEC: only alternatives leading to full replacement of animal experiments should be used. This chapter presents the three scientifically validated animal alternative methods for the assessment of embryotoxicity: the embryonic stem cell test (EST), the micromass (MM) assay, and the whole embryo culture (WEC) assay.
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