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. 2009 Dec;8(4):329-33.
doi: 10.1007/s12663-009-0080-1. Epub 2010 Apr 24.

In vitro evaluation of microbiological flora of orofacial infections

Munish Kohli  1 , Asha Mathur, Monica Kohli, Saif Rauf Siddiqui
Affiliations

In vitro evaluation of microbiological flora of orofacial infections

Munish Kohli et al. J Maxillofac Oral Surg. 2009 Dec.

Abstract

Objective: To assess the most common micro-organisms causing odontogenic infections and their antimicrobial susceptibility.

Methods: The study was conducted in 80 patients with orofacial infection. The pus sample was collected, cultured (aerobically and anaerobically) and stained for morphological study of the isolates. Antibiotic sensitivity test for the isolates were performed.

Results: A total of 109 micro-organisms were isolated, no pathogenic organism were isolated in 3 cases. Out of 109 micro-organism isolated, 107 bacteria and 2 fungi were identified. Pure aerobes were identified in 28(35%) of cases, pure anaerobes in 18(22.5%), mixed aerobes and anaerobes in 10(12.5%), mixed aerobes in 15(18.75%) and mixed anaerobes were isolated in 6(7.5%) cases. Among the entire pure gram positive isolates, ofloxacin was the most sensitive drug 83.33% followed by ciprofloxacin 76.2% and sparfloxacin 76.2%. The most resistant drugs were amoxicillin (92.85%) and ampicillin (92.85%). Cefotaxime was found sensitive in 75% of pure gram negative isolates.

Conclusion: Ofloxacin was the most sensitive drug followed by ciprofloxacin and sparfloxacin for pure gram positive isolates. The most resistant drugs were amoxicillin and ampicillin. The gram negative colonies were sensitive to Cefotaxime.

Keywords: Antibiotic sensitivity; Dentoalveolar abscess; Microbiological flora.

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