An update on the management of chronic inflammatory demyelinating polyneuropathy
- PMID: 23139706
- PMCID: PMC3487533
- DOI: 10.1177/1756285612457215
An update on the management of chronic inflammatory demyelinating polyneuropathy
Abstract
Chronic inflammatory demyelinating polyneuropathy (CIDP) is an immune mediated disorder of the peripheral nervous system with clinical features that include weakness, sensory loss, imbalance, pain and impaired ambulation which may lead to substantial disability. This review highlights current treatment strategies for CIDP, how best to utilize proven therapies such as intravenous immunoglobulin, oral prednisone, pulse dexamethasone, and plasma exchange, and when and how to use alternative immunosuppressive agents when first-line therapies are ineffective or poorly tolerated.
Keywords: CIDP; IVIg; demyelinating neuropathy; immune neuropathy; inflammatory polyneuropathy; treatment.
Conflict of interest statement
References
-
- Ahlmen J., Andersen G., Hallgren G., Peilot B. (1998) Positive effects of tacrolimus in a case of CIDP. Transplant Proc 30: 4194. - PubMed
-
- Alshekhlee A., Basiri K., Miles J., Ahmad S., Katirji B. (2010) Chronic inflammatory demyelinating polyneuropathy associated with tumor necrosis factor alpha antagonists. Muscle Nerve 41: 723–727 - PubMed
-
- Ashman E., Gronseth G. (2012) Level of evidence reviews. Three years of progress. Neurology 79: 13–14 - PubMed
-
- Axelson H., Oberg G., Askmark H. (2008) Successful repeated treatment with high dose cyclophosphamide and autologous blood stem cell transplantation in CIDP. J Neurol Neurosurg Psychiatry 79: 612–614 - PubMed
-
- Barnett M., Pollard J., Davies L., McLeod J. (1998) Cyclosporine A in resistant chronic inflammatory demyelinating polyradiculoneuropathy. Muscle Nerve 21: 454–460 - PubMed
LinkOut - more resources
Full Text Sources