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Review
. 2012 Nov 7;16(5):559-64.
doi: 10.1016/j.cmet.2012.10.007.

Gut microbiota composition and activity in relation to host metabolic phenotype and disease risk

Elaine Holmes  1 , Jia V Li, Julian R Marchesi, Jeremy K Nicholson
Affiliations
Free article
Review

Gut microbiota composition and activity in relation to host metabolic phenotype and disease risk

Elaine Holmes et al. Cell Metab. .
Free article

Abstract

The symbiotic gut microbiota modulate health and disease of the host through a series of transgenomic metabolic and immune regulatory axes. We explore connections between microbiome composition and function related to individual metabolic phenotypes and consider these interactions as possible targets for developing new personalized therapies and clinical management strategies.

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