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Comment
. 2012 Nov 9;48(3):327-8.
doi: 10.1016/j.molcel.2012.10.021.

Order from chaos in the nucleus

Zhixiong Xu  1 , Gary Felsenfeld
Affiliations
Comment

Order from chaos in the nucleus

Zhixiong Xu et al. Mol Cell. .

Abstract

Although it might appear that chromatin is randomly packed within the nucleus, recent data (Hou et al., 2012, in this issue of Molecular Cell) show that it is organized into defined and functionally important domains marked by preferred intradomain physical contacts, and with boundaries associated with insulator protein occupancy.

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