Giant cell tumor of the tendon sheath mimicking a primary intramedullary metatarsal tumor

Abstract

Giant cell tumor of the tendon sheath (GCTTS) is one of the most common benign soft tissue tumors in the extremities, and is frequently associated with bone abnormalities. Although extrinsic bone erosion is the most common bone abnormality associated with GCTTS, intraosseous invasion of GCTTS occurs rarely and may mimic a primary bone tumor, making diagnosis more challenging. We report an unusual imaging presentation of GCTTS mimicking a primary intramedullary metatarsal tumor and review the literature on the frequency of bone involvement of GCTTS.