Platinum chemotherapy for BRCA1-related breast cancer: do we need more evidence?
- PMID: 23146216
- PMCID: PMC4053124
- DOI: 10.1186/bcr3332
Platinum chemotherapy for BRCA1-related breast cancer: do we need more evidence?
Abstract
A recent prospective clinical trial provides further evidence that breast cancers arising in germline BRCA1 mutation carriers are highly sensitive to cisplatin chemotherapy. The potential significance of these data for the management of patients with BRCA1-related and BRCA2-related breast cancer is discussed.
Comment on
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Results of a phase II open-label, non-randomized trial of cisplatin chemotherapy in patients with BRCA1-positive metastatic breast cancer.Breast Cancer Res. 2012 Jul 20;14(4):R110. doi: 10.1186/bcr3231. Breast Cancer Res. 2012. PMID: 22817698 Free PMC article. Clinical Trial.
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