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Comment
. 2012 Nov;2(11):979-81.
doi: 10.1158/2159-8290.CD-12-0392.

Distinct epigenetic mechanisms distinguish TMPRSS2-ERG fusion-positive and -negative prostate cancers

Joshi J Alumkal  1 , James G Herman
Affiliations
Comment

Distinct epigenetic mechanisms distinguish TMPRSS2-ERG fusion-positive and -negative prostate cancers

Joshi J Alumkal et al. Cancer Discov. 2012 Nov.

Abstract

This issue of Cancer Discovery features an article that describes distinct epigenetic mechanisms that operate in TMPRSS2-ERG fusion-negative prostate cancers. This finding clarifies molecular features of these TMPRSS2-ERG fusion-negative tumors and may have implications for how to treat this prostate cancer subtype.

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Conflict of interest statement

Disclosure of Potential Conflicts of Interest

J.G. Herman has a commercial research grant from MDX Health and is a consultant/advisory board member of MDX Health. No potential conflicts of interest were disclosed by the other author.

Comment on

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