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Comment
. 2012 Nov 13:1:e00302.
doi: 10.7554/eLife.00302.

Histones join the fight against bacteria inside cells

Affiliations
Comment

Histones join the fight against bacteria inside cells

Roberto Kolter. Elife. .

Abstract

Experiments on Drosophila have shown that the histones that are normally bound to lipid droplets inside cells can be released to provide protection against infection.

Keywords: B. subtilis; D. melanogaster; E. coli; Mouse; anti-bacterial; histones; innate immunity; lipid droplet.

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Conflict of interest statement

Competing interests:The author declares that no competing interests exist

Figures

Figure 1.
Figure 1.
An early Drosophila embryo visualized using fluorescence microscopy. Nuclei have been false coloured blue and lipid droplets yellow. This embryo, which is ∼0.5 mm in length, is still a single cell containing many nuclei (a syncytium), and most of these are found on the surface. The detail on the right is an expanded head-on view of the surface inside the white rectangle and shows about 32 densely packed nuclei inside an area of about 25 × 25 µm.

Comment on

References

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