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Comment
. 2012 Dec;12(12):798.
doi: 10.1038/nrc3402. Epub 2012 Nov 15.

Lymphoma: Epigenetic therapy gains momentum

Sarah Seton-Rogers
Comment

Lymphoma: Epigenetic therapy gains momentum

Sarah Seton-Rogers. Nat Rev Cancer. 2012 Dec.
No abstract available

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Comment on

  • A selective inhibitor of EZH2 blocks H3K27 methylation and kills mutant lymphoma cells.
    Knutson SK, Wigle TJ, Warholic NM, Sneeringer CJ, Allain CJ, Klaus CR, Sacks JD, Raimondi A, Majer CR, Song J, Scott MP, Jin L, Smith JJ, Olhava EJ, Chesworth R, Moyer MP, Richon VM, Copeland RA, Keilhack H, Pollock RM, Kuntz KW. Knutson SK, et al. Nat Chem Biol. 2012 Nov;8(11):890-6. doi: 10.1038/nchembio.1084. Epub 2012 Sep 30. Nat Chem Biol. 2012. PMID: 23023262
  • EZH2 inhibition as a therapeutic strategy for lymphoma with EZH2-activating mutations.
    McCabe MT, Ott HM, Ganji G, Korenchuk S, Thompson C, Van Aller GS, Liu Y, Graves AP, Della Pietra A 3rd, Diaz E, LaFrance LV, Mellinger M, Duquenne C, Tian X, Kruger RG, McHugh CF, Brandt M, Miller WH, Dhanak D, Verma SK, Tummino PJ, Creasy CL. McCabe MT, et al. Nature. 2012 Dec 6;492(7427):108-12. doi: 10.1038/nature11606. Epub 2012 Oct 10. Nature. 2012. PMID: 23051747

References

    1. Nat Chem Biol. 2012 Nov;8(11):890-6 - PubMed
    1. Nature. 2012 Dec 6;492(7427):108-12 - PubMed
    1. ACS Med Chem Lett. 2012 Oct 19;3(12):1091-6 - PubMed

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