Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Comment
. 2012;9(11):e1001341.
doi: 10.1371/journal.pmed.1001341. Epub 2012 Nov 13.

New translational research provides insights into liver dysfunction in sepsis

John C Marshall  1
Affiliations
Comment

New translational research provides insights into liver dysfunction in sepsis

John C Marshall. PLoS Med. 2012.

Abstract

John Marshall discusses new research detailing the early onset in liver dysfunction in a rodent sepsis model, which he says can fundamentally change our understanding of this common clinical problem.

PubMed Disclaimer

Conflict of interest statement

The author has declared that no competing interests exist.

Comment on

References

    1. Safar P, DeKornfeld T, Pearson J, et al. (1961) Intensive care unit. Anesthesia 16: 275. - PubMed
    1. Baue AE (1975) Multiple, progressive, or sequential systems failure. A syndrome of the 1970s. Arch Surg 110: 779–781. - PubMed
    1. Bone RC, Balk RA, Cerra FB, Dellinger RP, Fein AM, et al. (1992) ACCP/SCCM consensus conference. Definitions for sepsis and organ failure and guidelines for the use of innovative therapies in sepsis. Chest 101: 1644–1655. - PubMed
    1. Bywaters EGL (1946) Anatomical changes in the liver after trauma. Clin Sci 6: 19. - PubMed
    1. Skillman JJ, Bushnell LS, Goldman H, Silen W (1969) Respiratory failure, hypotension, sepsis, and jaundice. A clinical syndrome associated with lethal hemorrhage and acute stress ulceration in the stomach. Am J Surg 117: 523–530. - PubMed