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Case Reports
. 2012 Dec;37(12):1184-5.
doi: 10.1097/RLU.0b013e318251e3f4.

Cardiac (18)F-FDG PET/CT with heparin detects infective vegetation in a patient with mechanical valve replacement

Alisa Klaipetch  1 , Osamu Manabe, Noriko Oyama-Manabe, Satoru Chiba, Masanao Naya, Shiro Yamada, Kenji Hirata, Hiroyuki Tsutsui, Nagara Tamaki
Affiliations
Case Reports

Cardiac (18)F-FDG PET/CT with heparin detects infective vegetation in a patient with mechanical valve replacement

Alisa Klaipetch et al. Clin Nucl Med. 2012 Dec.

Abstract

We report the usefulness of F-FDG PET/CT for the detection and therapy evaluation of the infective vegetation. A 64-year-old man with history of aortic valve replacement presented with 2 months of fever without identifiable cause. Echocardiogram showed no inflammation vegetation or abnormality of mechanical valve function. FDG PET/CT with 50 IU/kg IV heparin revealed focal uptakes near the mechanical aortic valve. After antibiotics therapy, fever was ameliorated, and FDG PET/CT findings showed markedly decreased uptake of the lesions. FDG PET/CT is a powerful tool to detect endocarditis even in patients with no anatomical abnormalities.

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