Three novel immunosuppressive steroidal glycosides from the stems of Stephanotis mucronata
- PMID: 23156986
Three novel immunosuppressive steroidal glycosides from the stems of Stephanotis mucronata
Abstract
Three novel and one known C21 steroidal glycosides were isolated from the stems of Stephanotis mucronata. Their structures were determined on the basis of chemical evidence and extensive spectroscopic methods. The four C21 steroidal glycosides displayed significant immunosuppressive activities in vitro.
Similar articles
-
Four new immunomodulating steroidal glycosides from the stems of Stephanotis mucronata.Steroids. 2006 Aug;71(8):683-90. doi: 10.1016/j.steroids.2006.04.007. Epub 2006 Jun 21. Steroids. 2006. PMID: 16793073
-
Two novel immunosuppressive pregnane glycosides from the roots of Stephanotis mucronata.Bioorg Med Chem Lett. 2006 Sep 1;16(17):4586-91. doi: 10.1016/j.bmcl.2006.06.005. Epub 2006 Jun 21. Bioorg Med Chem Lett. 2006. PMID: 16793265
-
Four new C-21 steroidal glycosides from the roots of Stephanotis mucronata and their immunological activities.Steroids. 2005 Nov;70(12):791-7. doi: 10.1016/j.steroids.2005.05.001. Steroids. 2005. PMID: 16005919
-
Three new immunomodulating C21-steroidal glycosides from the stems of Stephanotis mucronata.Chem Biodivers. 2005 Dec;2(12):1701-11. doi: 10.1002/cbdv.200590140. Chem Biodivers. 2005. PMID: 17191967
-
Chemistry and biological activity of steroidal glycosides from the Lilium genus.Nat Prod Rep. 2015 Mar;32(3):454-77. doi: 10.1039/c4np00063c. Nat Prod Rep. 2015. PMID: 25407469 Review.
Cited by
-
Cytotoxic polyhydroxylated pregnane glycosides from Cissampelos pareira var. hirsuta.RSC Adv. 2021 Dec 22;12(1):498-508. doi: 10.1039/d1ra07498a. eCollection 2021 Dec 20. RSC Adv. 2021. PMID: 35424474 Free PMC article.
-
Identification of C21 Steroidal Glycosides from Gymnema sylvestre (Retz.) and Evaluation of Their Glucose Uptake Activities.Molecules. 2021 Oct 29;26(21):6549. doi: 10.3390/molecules26216549. Molecules. 2021. PMID: 34770958 Free PMC article.
-
Is the pharmaceutical industry's preoccupation with the monotherapy drug model stifling the development of effective new drug therapies?Inflammopharmacology. 2018 Jun;26(3):861-879. doi: 10.1007/s10787-018-0488-7. Epub 2018 May 7. Inflammopharmacology. 2018. PMID: 29736688