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. 2012 Nov 15;12(5):607-9.
doi: 10.1016/j.chom.2012.11.003.

M cell differentiation: distinct lineage or phenotypic transition? Salmonella provides answers

Hiroshi Ohno  1 , Takashi Kanaya, Ifor R Williams
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M cell differentiation: distinct lineage or phenotypic transition? Salmonella provides answers

Hiroshi Ohno et al. Cell Host Microbe. .
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Abstract

Whether M cells arise from a distinct lineage or result from phenotypic transition is a matter of debate. In this issue of Cell Host & Microbe, Tahoun et al. (2012) provide evidence that SopB, a virulence factor of Salmonella enterica serovar Typhimurium, can induce phenotypic transition of lymphoid follicle-associated enterocytes into M cells.

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